Peptide Database

Peptide NameEndolysin A (EC 3.-.-.-) (Gene 10 protein) (Gp10) (Lysis protein) (Lysozyme)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length493 amino acids

Chemical FormulaC2419H3739N715O725S12

DescriptionStandard

        MTLIVTRDHAQWVHDMCRARAGNRYGYGGAFTLNPRDTTDCSGLVLQTAAWYGGRKDWIGNRYGSTESFRLDHKIVYDLGFRRLPPGGVAALGFTPVMLVGLQHGGGGRYSHTACTLMTMDIPGGPVKVSQRGVDWESRGEVNGVGVFLYDGARAWNDPLFHDFWYLDAKLEDGPTQSVDAAEILARATGLAYNRAVALLPAVRDGLIQADCTNPNRIAMWLAQIGHESDDFKATAEYASGDAYDTRTDLGNTPEVDGDGRLYKGRSWIMITGKDNYRDFSRWAHGRGLVPTPDYFVVHPLELSELRWAGIGAAWYWTVERPDINALSDRRDLETVTRRINGGLTNLDDRRRRYNLALAVGDQLLTLIGDDDELADPTIQRFIREIHGALFNTVVTQSPYGDPQNPDGSEPRSNLWQLHELIKNGDGMGHARYVEESARAGDLRELERVVRAAKGLGRDRSPEFIARARNVLAQIEAANPEYLQAYIARNGAL
    

Molecular Weight54821.70 Da

Isoelectric Point (pI)5.79

Net Charge (pH 7.0)-8.41

Net Charge (pH 7.4) -9.40

Charge Density (pH 7.0) -0.0171

GRAVY Index-0.44

Hydrophobic Moment 0.94

Boman Index-0.04

Instability Index32.06

Aliphatic Index 80.79

Aromaticity 0.0933

Extinction Coeff. Reduced 101300.00

Extinction Coeff. Oxidized 101550.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0331140 VERIFIED: YES

Provenance & Taxonomy

OrganismMycobacterium phage D29 [Virus]

FamilyL5likevirus endolysin A protein

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic