Peptide Database

Peptide NameUnnamed

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC124H224N50O28

DescriptionStandard

        GRKKRRQRRRGALWKSLLKNVGKA
    

Molecular Weight2863.42 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)10.76

Net Charge (pH 7.4) 10.54

Charge Density (pH 7.0) 0.4481

GRAVY Index-1.55

Hydrophobic Moment 0.66

Boman Index-0.70

Instability Index94.97

Aliphatic Index 69.17

Aromaticity 0.0417

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1356.32

LogP -14.64

H-bond Donors 52.0

H-bond Acceptors 39.0

Rotatable Bonds 106.0

Heavy Atoms 202.0

Ring Count 2.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0341339 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

FamilyDermaseptin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetTumor cells: H157

Activity21.6 μM

MethodIC50

RECORD: Rec_0341587 VERIFIED: YES