Peptide Database

Peptide NameSyn-BNP (2. Ala5)

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC46H89N15O10

DescriptionStandard

        KLGVALKRK
    

Molecular Weight1012.29 Da

Isoelectric Point (pI)11.26

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.4175

GRAVY Index-0.33

Hydrophobic Moment 0.47

Boman Index-0.30

Instability Index26.24

Aliphatic Index 130.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 436.08

LogP -2.67

H-bond Donors 16.0

H-bond Acceptors 14.0

Rotatable Bonds 38.0

Heavy Atoms 71.0

Ring Count 0.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0077916 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

Other ModsHMA

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetCryp. neoformans

Activity2 μg/mL

MethodMIC

RECORD: Rec_0087643 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermC14OH

C-TermNone

Other Modsk=D-Lys; v=D-Val

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic

RECORD: Rec_0129867 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermC14OH

C-TermNone

Other Modsk=D-Lys; v=D-Val

Bio-Activity Profile

Function

Antimicrobial Anticancer Cytotoxic

RECORD: Rec_0345832 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

Other ModsHMA

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetCandida albicans

Activity16 μg/mL

MethodMIC

RECORD: Rec_0384224 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermC14OH

C-TermNone

Other Modsk=D-Lys; v=D-Val

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetHT-29

Activity>128 μg/mL

MethodLC