Peptide Database

Peptide NameSLAY-screened peptide P773

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC85H133N27O19S3

DescriptionStandard

        AMAHCGKPIVPHHRLCY
    

Molecular Weight1933.33 Da

Isoelectric Point (pI)8.91

Net Charge (pH 7.0)2.04

Net Charge (pH 7.4) 1.66

Charge Density (pH 7.0) 0.1197

GRAVY Index0.01

Hydrophobic Moment 0.43

Boman Index0.10

Instability Index8.58

Aliphatic Index 74.71

Aromaticity 0.0588

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 705.53

LogP -4.56

H-bond Donors 26.0

H-bond Acceptors 27.0

Rotatable Bonds 57.0

Heavy Atoms 134.0

Ring Count 6.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0249971 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/