MYP_081704
Basic Information
KLW-K11-Nala
Anticancer
Anticancer Cytotoxic anticancer activity Cytotoxic
Antimicrobial
Antimicrobial Antibacterial
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Toxicity / Safety Cytotoxicity Cytotoxic
Venom / Toxin General toxin Cytotoxic
Venom / Toxin General toxin Toxic
not Standard
18 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
KWKKLLKKLLXLLKKLLK
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0351533 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 38.9%, E 0.0%, T 33.3%, C 27.8% [Linear]
residue-level stereochemical modification [Mixed]
None
Amidation
Bio-Activity Profile
Toxic Antimicrobial Hemolytic
RECORD: Rec_0373716 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 11
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli KCTC 1682
4 μM
MIC
RECORD: Rec_0398271 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X=NAla
Bio-Activity Profile
Antimicrobial Anticancer
A549
0.6 μM
IC50
RECORD: Rec_0408093 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X=NAla
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: SK-OV-3
0.5 μM
IC50
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