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MYP_081704
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Basic Information
KLW-K11-Nala
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
not Standard
18 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
KWKKLLKKLLXLLKKLLK
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0218051 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 11
Bio-Activity Profile
Antimicrobial Antibacterial
Human skin melanoma SK-MEL-2
0.6 μM
IC50
PMID16142907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16142907/
RECORD: Rec_0257733 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 11
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus subtilis KCTC 3068
4 μM
MIC
PMID16142907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16142907/
RECORD: Rec_0266273 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
a=Nala (Ala-peptoid)
Bio-Activity Profile
Antimicrobial
Human erythrocytes
100 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/16142907/ PMID16142907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16142907/
RECORD: Rec_0283417 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 11
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa KCTC 1637
4 μM
MIC
PMID16142907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16142907/
RECORD: Rec_0301110 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 11
Bio-Activity Profile
Hemolytic
human erythrocytes
100 μM
Hemolysis
PMID16142907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16142907/
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