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MYP_081704
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Basic Information
KLW-K11-Nala
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
not Standard
18 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
KWKKLLKKLLXLLKKLLK
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0087369 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 11
Bio-Activity Profile
Antimicrobial Antibacterial
Human lung carcinoma A549
0.6 μM
IC50
PMID16142907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16142907/
RECORD: Rec_0154650 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
a=Nala (Ala-peptoid)
Bio-Activity Profile
Antimicrobial
Human erythrocytes
50 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/16142907/ PMID16142907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16142907/
RECORD: Rec_0155274 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X=NAla
Bio-Activity Profile
Antimicrobial Anticancer
SK-MEL-2
0.6 μM
IC50
PMID16142907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16142907/
RECORD: Rec_0181854 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 11
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus epidermidis KCTC 1917
4 μM
MIC
PMID16142907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16142907/
RECORD: Rec_0193922 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 11
Bio-Activity Profile
Antimicrobial Antibacterial
Salmonella typhimurium KCTC 1926
4 μM
MIC
PMID16142907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16142907/
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