Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length203 amino acids

Chemical FormulaC1037H1599N245O300S10

DescriptionStandard

        MLYLAFSEYFFQTSSFAYYTAGAFNITIAEETCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPVISLKQDSFTVDIQGSMEVFAVLPDSTTQSLFTMNVAANTSIALNIFDQKLMGSLCLNRLQFSLAHSNVGFFEISLLENILSYILQTEVIPSANAKLSKGFPLPNLANVTLMRPHITIAQGYMLISTDVHYRH
    

Molecular Weight22618.90 Da

Isoelectric Point (pI)5.06

Net Charge (pH 7.0)-6.15

Net Charge (pH 7.4) -6.64

Charge Density (pH 7.0) -0.0303

GRAVY Index0.39

Hydrophobic Moment 0.55

Boman Index0.25

Instability Index48.07

Aliphatic Index 101.87

Aromaticity 0.1232

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0282939 VERIFIED: NO

Provenance & Taxonomy

OrganismFalco tinnunculus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria

MethodQualitative functional evidence