Peptide Database

Peptide NameHuman beta defensin 3

Function Ontology

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Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC171H285N51O51S4

DescriptionStandard

        GIISTVQRYFCKVRSGRCALVSCLPKEEHIGSCSLTG
    

Molecular Weight3999.66 Da

Isoelectric Point (pI)8.92

Net Charge (pH 7.0)2.81

Net Charge (pH 7.4) 2.49

Charge Density (pH 7.0) 0.0760

GRAVY Index0.19

Hydrophobic Moment 0.69

Boman Index0.04

Instability Index59.36

Aliphatic Index 89.46

Aromaticity 0.0541

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1648.08

LogP -19.21

H-bond Donors 64.0

H-bond Acceptors 59.0

Rotatable Bonds 133.0

Heavy Atoms 277.0

Ring Count 4.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0267589 VERIFIED: YES

Provenance & Taxonomy

OrganismMyotis davidii [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)