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MYP_081613
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Basic Information
Figainin 2, Figainin-02
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Antiviral ▸ Anti-Flavivirus ▸ Anti-Dengue virus
Enzyme modulation ▸ Enzyme inhibition ▸ Infection inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
28 amino acids
C142H236N36O33S
Standard
Sequence
FLGAILKIGHALAKTVLPMVTNAFKPKQ
Physicochemical Analysis
3007.68 Da
10.48
3.84
3.58
0.1373
0.57
0.57
0.28
3.59
118.57
0.0714
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1090.84
-5.95
36.0
39.0
99.0
212.0
5.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0409070 VERIFIED: YES
Provenance & Taxonomy
Boana raniceps [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral Antiparasitic Antiprotozoal Antifungal
Klebsiella pneumoniae
16 μM
MIC
PMID32443921 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32443921/
RECORD: Rec_0418109 VERIFIED: YES
Provenance & Taxonomy
Boana raniceps [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral Antiparasitic Antiprotozoal Antifungal
Candida albicans ATCC 90028
PMID32443921 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32443921/
RECORD: Rec_0421489 VERIFIED: YES
Provenance & Taxonomy
Boana raniceps [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
PaperPubMed PMID: 32443921 PMID32443921 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32443921/
RECORD: Rec_0423592 VERIFIED: YES
Provenance & Taxonomy
Boana raniceps [Animal]
192750
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-DENV Infection inhibition
Dengue Serotype 4 Virus(DENV4) | Huh7 cells
20.8 μM
EC50
Mammalian: 1.1 h; Yeast: 3 min; E. coli: 2 min
PaperBiological Properties of a Novel Multifunctional Host Defense Peptide from the Skin Secretion of the Chaco Tree Frog, Boana raniceps. | Santana CJC, Magalhães ACM, Prías-Márquez CA, Falico DA, Dos Santos Júnior ACM, Lima BD, Ricart CAO, de Pilger DRB, Bonotto RM, Moraes CB, Freitas-Júnior LH, Álvares ADCM, Freitas SM, Luz IS, Pires OR Jr, Fontes W, Castro MS. | Biomolecules. 2020 May 20;10(5):790. | DOI:10.3390/biom10050790 | PMID:32443921 PMID32443921 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32443921/
RECORD: Rec_0426151 VERIFIED: YES
Provenance & Taxonomy
Boana raniceps [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral Antiparasitic Antiprotozoal Antifungal
Staphylococcus epidermidis ATCC 12228
4 μM
MIC
PMID32443921 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32443921/
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