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MYP_081613
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Basic Information
Figainin 2, Figainin-02
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Antiviral ▸ Anti-Flavivirus ▸ Anti-Dengue virus
Enzyme modulation ▸ Enzyme inhibition ▸ Infection inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
28 amino acids
C142H236N36O33S
Standard
Sequence
FLGAILKIGHALAKTVLPMVTNAFKPKQ
Physicochemical Analysis
3007.68 Da
10.48
3.84
3.58
0.1373
0.57
0.57
0.28
3.59
118.57
0.0714
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1090.84
-5.95
36.0
39.0
99.0
212.0
5.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0275487 VERIFIED: YES
Provenance & Taxonomy
Boana raniceps [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral Antiparasitic Antiprotozoal Antifungal
Klebsiella pneumoniae ATCC 13883
8 μM
MIC
PMID32443921 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32443921/
RECORD: Rec_0279705 VERIFIED: YES
Provenance & Taxonomy
Boana raniceps [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral Antiparasitic Antiprotozoal Antifungal
Trypanosoma cruzi
6.32 μM
IC50
PMID32443921 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32443921/
RECORD: Rec_0295996 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Boana raniceps [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral Anticancer Antiparasitic
Gram- Escherichia coli ATCC 25922, Klebsiella pneumoniae ATCC 13883
8 μM
MIC
PaperBiological Properties of a Novel Multifunctional Host Defense Peptide From the Skin Secretion of the Chaco Tree Frog, Boana raniceps
RECORD: Rec_0363196 VERIFIED: YES
Provenance & Taxonomy
Boana raniceps [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
chikungunya virus (CHIKV):inhibition of viral infection in Huh7 cells
17 μM
EC50
PaperPubMed PMID: 32443921 PMID32443921 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32443921/
RECORD: Rec_0366442 VERIFIED: YES
Provenance & Taxonomy
Boana raniceps [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral Antiparasitic Antiprotozoal Antifungal
Human hepatocellular carcinoma Huh7
PMID32443921 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32443921/
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