Peptide Database

Peptide NameCecropin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length43 amino acids

Chemical FormulaC195H335N69O54S6

DescriptionStandard

        VTCDLLSAEAKGVKVNHAACAAHCLLKRKRGGYCNRRICVCRN
    

Molecular Weight4702.57 Da

Isoelectric Point (pI)9.55

Net Charge (pH 7.0)6.85

Net Charge (pH 7.4) 6.44

Charge Density (pH 7.0) 0.1593

GRAVY Index-0.09

Hydrophobic Moment 0.58

Boman Index-0.15

Instability Index46.92

Aliphatic Index 86.28

Aromaticity 0.0233

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2021.02

LogP -23.74

H-bond Donors 79.0

H-bond Acceptors 69.0

Rotatable Bonds 160.0

Heavy Atoms 324.0

Ring Count 3.0

Amide Bonds 45.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0168250 VERIFIED: YES

Provenance & Taxonomy

OrganismTribolium castaneum [Animal]

FamilyCecropin

Tax ID7070

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive

TargetStaphylococcus aureus

Activity13.2±1.8 μg/mL

MethodMIC

RECORD: Rec_0239462 VERIFIED: YES