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MYP_081548
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Basic Information
CAP18
Anticancer
Anticancer ▸ Anti-proliferative
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
37 amino acids
C202H356N64O47
Standard
Sequence
GLRKRLRKFRNKIKEKLKKIGQKIQGLLPKLAPRTDY
Physicochemical Analysis
4433.39 Da
11.54
11.75
11.53
0.3177
-1.10
0.67
-0.43
31.00
97.57
0.0541
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1881.35
-14.01
67.0
59.0
163.0
313.0
4.0
39.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0016079 VERIFIED: YES
Provenance & Taxonomy
Oryctolagus cuniculus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ML-35p(100 mM NaCl
0.09 μM
MIC
PMID11557478;10768969;26656394;30245684;29852015 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11557478/
RECORD: Rec_0021876 VERIFIED: YES
Provenance & Taxonomy
Oryctolagus cuniculus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Campylobacter jejuni NCTC 11168
1 μg/mL
MIC
PMID11557478;10768969;26656394;30245684;29852015 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11557478/
RECORD: Rec_0021899 VERIFIED: YES
Provenance & Taxonomy
Oryctolagus cuniculus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0039576 VERIFIED: YES
Provenance & Taxonomy
Oryctolagus cuniculus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ML-35p
0.05 μM
MIC
PMID11557478;10768969;26656394;30245684;29852015 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11557478/
RECORD: Rec_0040462 VERIFIED: YES
Provenance & Taxonomy
Oryctolagus cuniculus [Animal]
Cathelicidin
9986
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Refer pmid:-10768969[ Pseudomonas aeruginosa PAO1 (
1.24 μM
MIC
PMID11557478 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11557478/
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