Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC376H638N100O108S7

DescriptionStandard

        MKLLLLLLTVTLLLAQVTPVTKCWGKSGRCRTTCKKREVYYILCKTEAKCCVDPKYVPVRSKLTDTNTSLESTSAV
    

Molecular Weight8512.15 Da

Isoelectric Point (pI)9.44

Net Charge (pH 7.0)7.44

Net Charge (pH 7.4) 7.11

Charge Density (pH 7.0) 0.0979

GRAVY Index0.08

Hydrophobic Moment 0.61

Boman Index-0.01

Instability Index21.79

Aliphatic Index 101.18

Aromaticity 0.0526

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3374.07

LogP -31.60

H-bond Donors 128.0

H-bond Acceptors 123.0

Rotatable Bonds 285.0

Heavy Atoms 591.0

Ring Count 8.0

Amide Bonds 77.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0170896 VERIFIED: NO

Provenance & Taxonomy

OrganismPapio anubis [Animal]

FamilyBeta-defensin; Defensin

Tax ID9555

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic

RECORD: Rec_0200369 VERIFIED: NO