Peptide Database

Peptide Namealpha-2 gliadin (p62-p73; E65)

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC66H99N15O19

DescriptionStandard

        PQPELPYPQPQL
    

Molecular Weight1406.58 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.04

Net Charge (pH 7.4) -1.10

Charge Density (pH 7.0) -0.0866

GRAVY Index-1.31

Hydrophobic Moment 0.10

Boman Index-0.03

Instability Index130.23

Aliphatic Index 65.00

Aromaticity 0.0833

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 521.07

LogP -3.12

H-bond Donors 14.0

H-bond Acceptors 18.0

Rotatable Bonds 37.0

Heavy Atoms 100.0

Ring Count 6.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0238921 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDeamidation; Reported substitutions/positions: E65

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman intestinal T cells / HLA-DQ2

MethodIntestinal T-cell assay

RECORD: Rec_0340539 VERIFIED: YES