Peptide Database

Peptide NameNisin A

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC114H203N31O37S6

DescriptionStandard

        VTSKSLCTPGCKTGILMTCAIKTATCGC
    

Molecular Weight2792.41 Da

Isoelectric Point (pI)8.78

Net Charge (pH 7.0)2.68

Net Charge (pH 7.4) 2.39

Charge Density (pH 7.0) 0.0958

GRAVY Index0.66

Hydrophobic Moment 0.37

Boman Index0.20

Instability Index15.01

Aliphatic Index 73.21

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1080.13

LogP -15.17

H-bond Donors 44.0

H-bond Acceptors 46.0

Rotatable Bonds 91.0

Heavy Atoms 188.0

Ring Count 1.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0067710 VERIFIED: YES

Provenance & Taxonomy

OrganismStreptococcus suis [Bacterium]

FamilyBacteriocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)