‹ ›
MYP_081437
← PREVIOUS NEXT → BACK
Basic Information
Cycloviolacin-O8 (Cyclotide c1; Plant defensin)
Anticancer
Antimicrobial
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Insecticidal/Pest control ▸ Insecticidal activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
30 amino acids
C136H221N35O41S6
Standard
Sequence
GTLPCESCVWIPCISSVVGCSCKSKVCYKN
Physicochemical Analysis
3194.81 Da
8.33
1.70
1.40
0.0566
0.50
0.34
0.17
33.67
77.67
0.0667
6990.00
7365.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1205.49
-13.78
48.0
49.0
100.0
218.0
5.0
30.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0228785 VERIFIED: YES
Provenance & Taxonomy
Viola odorata [Plant]
Cyclotide
97441
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
multiple disulfide bonds reported, sites not specified
Bio-Activity Profile
Antimicrobial Antiparasitic
PaperPubMed PMID 10600388 PMID10600388 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10600388/
RECORD: Rec_0296205 VERIFIED: YES
Provenance & Taxonomy
Viola odorata [Plant]
97441
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiparasitic
nematode parasites of sheep (e.g. Haemonchus contortus
PaperPlant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif. PMID10600388 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10600388/
RECORD: Rec_0302758 VERIFIED: YES
Provenance & Taxonomy
Viola odorata [Plant]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
5-21; 9-23; 14-28
Bio-Activity Profile
Insecticidal Cytotoxic
PaperPubMed PMID: 16872274 | PubMed PMID: 10600388 PMID16872274;10600388 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16872274/
RECORD: Rec_0364334 VERIFIED: YES
Provenance & Taxonomy
Viola odorata [Plant]; Insecta [Animal]
33090; 50557
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID10600388 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10600388/
RECORD: Rec_0365495 VERIFIED: NO
Provenance & Taxonomy
Viola odorata [Plant]
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
4-20; 8-22; 13-27
Bio-Activity Profile
Antimicrobial
FIRST PREV 1 2
Showing 5 records · Page 2 of 2