Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length98 amino acids

Chemical FormulaC464H767N115O125S4

DescriptionStandard

        MKSKRMEFHNKFLIVSAMLAVISWLSLGVVSFPMLAGTLGISTKAAATVVNLISAYSTVTAVISIVGAITGVGSIGSGIAATVLYILKKKSAAQAALW
    

Molecular Weight10085.01 Da

Isoelectric Point (pI)10.30

Net Charge (pH 7.0)6.58

Net Charge (pH 7.4) 6.30

Charge Density (pH 7.0) 0.0672

GRAVY Index1.02

Hydrophobic Moment 0.49

Boman Index0.40

Instability Index15.36

Aliphatic Index 127.45

Aromaticity 0.0714

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3772.93

LogP -31.91

H-bond Donors 136.0

H-bond Acceptors 137.0

Rotatable Bonds 334.0

Heavy Atoms 708.0

Ring Count 11.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0020789 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus pseudopneumoniae [Bacterium]

FamilyBacteriocin

Tax ID257758

Structure & Mods

Confighead-to-tail cyclic bacteriocin scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsCyclized peptide scaffold annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Non-hemolytic Non-ribosomal

RECORD: Rec_0220404 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus pseudopneumoniae [Bacterium]

FamilyCircular bacteriocin

Structure & Mods

Configcyclic peptide topology reported [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal