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MYP_081380
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Basic Information
Nigrocin-2SCc
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
21 amino acids
C89H160N24O25S3
Standard
Sequence
GILSNVLGMGKKIVCGLSGLC
Physicochemical Analysis
2062.56 Da
8.90
1.74
1.50
0.0828
1.17
0.51
0.41
2.52
139.05
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
780.91
-7.43
29.0
30.0
72.0
141.0
0.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0062969 VERIFIED: YES
Provenance & Taxonomy
Odorrana schmackeri [Animal]
Nigrocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
15-21
Bio-Activity Profile
Antimicrobial
Escherichia coli
70 μM
MIC
PaperNigrocin-2 peptides from Chinese Odorrana frogs--integration of UPLC/MS/MS with molecular cloning in amphibian skin peptidome analysis
RECORD: Rec_0106846 VERIFIED: YES
Provenance & Taxonomy
Amphibia [Animal]
8292
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID20158520 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20158520/
RECORD: Rec_0137088 VERIFIED: YES
Provenance & Taxonomy
Odorrana schmackeri [Animal]
Nigrosin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
15-21
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
100.0 μM
MIC
PaperL. Wang et al. / FEBS Journal 277 (2010) 1519-1531. Nigrocin-2 peptides from Chinese Odorrana frogs - integration of UPLC/MS/MS with molecular cloning in amphibian skin peptidome analysis Evidence URLhttps://www.uniprot.org/uniprotkb/B7UEM1/entry
RECORD: Rec_0147630 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0161694 VERIFIED: NO
Provenance & Taxonomy
Odorrana schmackeri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
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