Peptide Database

Peptide NameS-type Pyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length637 amino acids

Chemical FormulaC2951H4661N807O931S12

DescriptionStandard

        HDLPAGTPADVQSAINQVKQAGGLMSVDLRKLRPAAGYPWDPTVAWDPVFVYFPAKAVSDSDLSAGSLPETVPVHSRIQDDVHDGAQFISITGSGSQPYNLPVIKATPTPRGPYYTIGHLPGPMGPYTFTFNANAPHSELHFARDEEKVSALHPAGFTVGANTTDCIVVFPEGSGLEPLYFSMTVILPEGPLKQRQEEENQARAKADAEAEAKAKAEAEAKAKEKAEREALFARAGVVPAPTYTPEMVKSAEAALGAAGVMVLGQTPGAMQLSVAGGGVLTATGEVLSSLGAAVGRAIASLGATATAGTAGPMVAAASAILFPPAAGEGSDRVPGRDLNAMFALNAQLLAGQDVKIEPGATSVNLPERGHLVNSNGQMALQLLKTGDTLPAAVPVLNAVRDAATGLDRITVPAVAGAPERTILVNPAPSPAAPSDTASPPPSVPVTPVHTGTEIKPVETITVTTTPAADIGGLQDFIYWRPDAAGTGVEPVYVMLSGLYGETNAKGKYSGRDYNSDKAGGPIQDLDWKTATIDREGVDKVKLHTGRFGESAENVVMIDRLEKILKGELQPTDTDKRFYTHEIRELERYRAVGVLDGVSPDDDGVTWNNTHTATLEDYKLSSDRSLLYTPEALKAGDE
    

Molecular Weight66725.21 Da

Isoelectric Point (pI)4.95

Net Charge (pH 7.0)-24.09

Net Charge (pH 7.4) -25.08

Charge Density (pH 7.0) -0.0378

GRAVY Index-0.20

Hydrophobic Moment 0.77

Boman Index0.08

Instability Index32.95

Aliphatic Index 81.87

Aromaticity 0.0581

Extinction Coeff. Reduced 52830.00

Extinction Coeff. Oxidized 52830.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0349011 VERIFIED: NO

Provenance & Taxonomy

OrganismSalmonella enterica [Bacterium]

FamilyColicin/Bacteriocin

Tax ID28901

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence