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MYP_081355
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Basic Information
Cecropin-B (Insects, animals)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
35 amino acids
C177H303N51O42
Standard
Sequence
KWKIFKKIEKVGRNIRNGIIKAGPAVAVLGEAKAL
Physicochemical Analysis
3817.62 Da
10.73
6.76
6.54
0.1931
0.00
0.93
0.02
22.08
117.14
0.0571
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1526.44
-9.82
53.0
49.0
135.0
270.0
4.0
36.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0088059 VERIFIED: YES
Provenance & Taxonomy
Antheraea pernyi [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
J82
97.93 μg/mL
IC50
PMID18315881 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18315881/
RECORD: Rec_0092278 VERIFIED: YES
Provenance & Taxonomy
Antheraea pernyi [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
J82
196.3 μg/mL
Cytotoxicity assay
PMID18315881 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18315881/
RECORD: Rec_0110064 VERIFIED: YES
Provenance & Taxonomy
Antheraea pernyi [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
486P
87.47 μg/mL
IC50
PMID18315881 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18315881/
RECORD: Rec_0117868 VERIFIED: YES
Provenance & Taxonomy
Antheraea pernyi [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Bacillus subtilis Bsll
17 μM
MIC
PMID6754375;2962676 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/6754375/
RECORD: Rec_0120412 VERIFIED: YES
Provenance & Taxonomy
Antheraea pernyi [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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