Peptide Database

Peptide NameCircularin A uberolysin family circular bacteriocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length107 amino acids

Chemical FormulaC511H816N126O138S2

DescriptionStandard

        MTYSVKGRAVSFGALLAVGAALLASYAFLLGILPEMNLVKEFNLSTVAAAQVFAWLDYISWGVSLVALIGSLGTGGAALVAAAGAQGIRKYLTDLAKEKGKKAAIAY
    

Molecular Weight10996.84 Da

Isoelectric Point (pI)9.52

Net Charge (pH 7.0)3.50

Net Charge (pH 7.4) 3.26

Charge Density (pH 7.0) 0.0327

GRAVY Index0.79

Hydrophobic Moment 0.66

Boman Index0.35

Instability Index7.65

Aliphatic Index 121.50

Aromaticity 0.1028

Extinction Coeff. Reduced 18450.00

Extinction Coeff. Oxidized 18450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4159.19

LogP -31.43

H-bond Donors 147.0

H-bond Acceptors 144.0

Rotatable Bonds 361.0

Heavy Atoms 777.0

Ring Count 14.0

Amide Bonds 110.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0414702 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus thuringiensis [Bacterium]

FamilyCircular bacteriocin

Structure & Mods

Configcyclic peptide topology reported [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal