Peptide Database

Peptide NameDEFA1B isoform 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC447H713N125O129S7

DescriptionStandard

        MSTLAILAAILLVALQAQAEPLQARADEVAAAPEQIPADNPEVVVSLAWDESLAPKHPGSRKNVACYCRIPACLAGERRYGTCIYQGRLWAFCC
    

Molecular Weight10126.66 Da

Isoelectric Point (pI)5.70

Net Charge (pH 7.0)-1.46

Net Charge (pH 7.4) -1.83

Charge Density (pH 7.0) -0.0155

GRAVY Index0.22

Hydrophobic Moment 0.49

Boman Index0.12

Instability Index57.66

Aliphatic Index 99.89

Aromaticity 0.0638

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4011.19

LogP -36.37

H-bond Donors 142.0

H-bond Acceptors 136.0

Rotatable Bonds 320.0

Heavy Atoms 708.0

Ring Count 16.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0298155 VERIFIED: NO

Provenance & Taxonomy

OrganismPan troglodytes [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicidal Antibiotic Defensin Non-hemolytic Non-ribosomal