Peptide Database

Peptide NameCycloviolacin H4

Function Ontology

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Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC128H211N31O38S6

DescriptionStandard

        IPCGESCVYIPCISSLLGCSCKSKVCYK
    

Molecular Weight2984.62 Da

Isoelectric Point (pI)8.32

Net Charge (pH 7.0)1.70

Net Charge (pH 7.4) 1.40

Charge Density (pH 7.0) 0.0607

GRAVY Index0.67

Hydrophobic Moment 0.34

Boman Index0.20

Instability Index28.13

Aliphatic Index 90.36

Aromaticity 0.0714

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1088.41

LogP -11.01

H-bond Donors 44.0

H-bond Acceptors 46.0

Rotatable Bonds 95.0

Heavy Atoms 203.0

Ring Count 4.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0349257 VERIFIED: YES

Provenance & Taxonomy

OrganismMelicytus ramiflorus [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)