Peptide Database

Peptide NameCircularin A uberolysin family circular bacteriocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC537H879N131O152S4

DescriptionStandard

        MKNSNLFKIASITGVVSLFAIATFLMGSSEGIAGLASIDFSSGHQFALDLATNLGISKKTAYVAIGVIMTTGDVLTILSLLAVVLGGTGLITAAMVATAKKLAKKYGKKYAAEW
    

Molecular Weight11730.77 Da

Isoelectric Point (pI)9.65

Net Charge (pH 7.0)4.58

Net Charge (pH 7.4) 4.29

Charge Density (pH 7.0) 0.0402

GRAVY Index0.75

Hydrophobic Moment 0.64

Boman Index0.34

Instability Index7.93

Aliphatic Index 117.37

Aromaticity 0.0789

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 9970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4480.44

LogP -39.72

H-bond Donors 159.0

H-bond Acceptors 162.0

Rotatable Bonds 396.0

Heavy Atoms 824.0

Ring Count 11.0

Amide Bonds 117.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0372767 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus haynesii [Bacterium]

FamilyBacteriocin

Tax ID1925021

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitynoncanonical stereochemical modification [Modified]

Other ModsCyclized peptide scaffold annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Non-hemolytic Non-ribosomal