Peptide Database

Peptide NameEndolysin (EC 4.2.2.n2) (Lysis protein) (Lysozyme) (Transglycosylase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Lyase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length157 amino acids

Chemical FormulaC767H1205N215O233S2

DescriptionStandard

        MAKFEVTTQRKAFLDALAVGEGTDNGKQKTNNHGYDVIVGGELFTDYSKHPAKLVRLRPGLSSTAAGRYQLLSKYYGHYKDLLGLPDFSPASQDQIALQQISERRALADIDAGRIADAVKKCNTIWASLPGSPYGQRTETLDDFLSYFRKAGGKVAE
    

Molecular Weight17230.20 Da

Isoelectric Point (pI)8.92

Net Charge (pH 7.0)2.77

Net Charge (pH 7.4) 2.33

Charge Density (pH 7.0) 0.0176

GRAVY Index-0.47

Hydrophobic Moment 0.68

Boman Index-0.05

Instability Index29.56

Aliphatic Index 78.41

Aromaticity 0.0955

Extinction Coeff. Reduced 17420.00

Extinction Coeff. Oxidized 17420.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7256.04

LogP -76.39

H-bond Donors 253.0

H-bond Acceptors 241.0

Rotatable Bonds 575.0

Heavy Atoms 1217.0

Ring Count 25.0

Amide Bonds 168.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0419379 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage sortkaff [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Lyase Cytolytic Non-hemolytic