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MYP_081123
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Basic Information
[K22,25,27]-SMAP-29 (SMAP-29 peptide derivative)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
28 amino acids
C144H260N54O31
Standard
Sequence
RGLRRLGRKIAHGVKKYGPTVKRIKRKA
Physicochemical Analysis
3243.95 Da
12.00
11.84
11.58
0.4229
-1.08
1.07
-0.50
39.34
83.57
0.0357
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1436.89
-13.30
55.0
44.0
117.0
229.0
3.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0238990 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PMID11467858 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11467858/
RECORD: Rec_0242655 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Pseudomonas aeruginosa
4 μM
MIC
PMID11467858 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11467858/
RECORD: Rec_0267563 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
4.0 μM
MIC
PMID11467858 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11467858/
RECORD: Rec_0278040 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
[100 mM NaCl]: Bacillus subtilis
4.0 μM
MIC
PMID11467858 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11467858/
RECORD: Rec_0282423 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 28.6%, E 7.1%, T 32.1%, C 32.1% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
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