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MYP_081123
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Basic Information
[K22,25,27]-SMAP-29 (SMAP-29 peptide derivative)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
28 amino acids
C144H260N54O31
Standard
Sequence
RGLRRLGRKIAHGVKKYGPTVKRIKRKA
Physicochemical Analysis
3243.95 Da
12.00
11.84
11.58
0.4229
-1.08
1.07
-0.50
39.34
83.57
0.0357
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1436.89
-13.30
55.0
44.0
117.0
229.0
3.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0073734 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
PMID11467858 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11467858/
RECORD: Rec_0085023 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
[No NaCl]: Escherichia coli
6 μM
MIC
PMID11467858 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11467858/
RECORD: Rec_0086789 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Salmonella typhimurium
2.0 μM
MIC
PMID11467858 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11467858/
RECORD: Rec_0106411 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
100 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/11467858/ PMID11467858 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11467858/
RECORD: Rec_0119347 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Micrococcus luteus
2 μM
MIC
PMID11467858 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11467858/
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