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MYP_081047
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Basic Information
Guanylate-binding protein 1 (EC 3.6.5.-) (GTP-binding protein 1) (GBP-1) (Guanine nucleotide-binding protein 1) (Interferon-induced guanylate-binding protein 1)
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Listeria
Antimicrobial ▸ Antibiotic activity
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Enzyme / Catalytic activity ▸ Hydrolase
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
590 amino acids
C2991H4805N821O918S27
Standard
Sequence
MASEIHMTGPMCLIENTNGRLMVNPEALKILSAITQPVVVVAIVGLYRTGKSYLMNKLAGKKKGFSLGSTVQSHTKGIWMWCVPHPKKPGHVLVLLDTEGLGDVEKGDNQNDSWIFALAILLSSTFVYNSMGTINQQAMDQLHYVTELTHRIRSKSSPDENENEDSADFVSFFPDFVWTLRDFSLDLEADGQPITADEYLTYSLKLKKGTSEKDKTFNLPRLCIRKFFPKKKCFVFDRPVHRKKLAQLEKLHDEELDPEFVQQVADFCSYIFSNSKTKTLSGGIKVNGPRLESLVLTYVNAISSGDLPCMENAVLALAQIENSAAVQKAVAHYEQQMGQKVQLPTETLQELLDLHRDSEREAIEVFIRSSFKDVDHLFQKELAAQLEKKRDDFCKQNQEASSDRCSALLQDIFSPLEEEVKMGIYSKPGGYRLFIQKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQASTKMLQEIQRKNEQMMEQKERSYQEHLKQLTEKMERDRAQLLKEQERTLALKLQEQERLLKEGFQTESRKMQNEIQDLQKKMRQRRTCTIS
Physicochemical Analysis
67819.85 Da
6.38
-3.42
-4.60
-0.0058
-0.59
0.66
-0.11
43.57
82.31
0.0712
44350.00
44850.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0197658 VERIFIED: NO
Provenance & Taxonomy
Chlorocebus aethiops [Animal]
TRAFAC class dynamin-like GTPase; GB1 RHD3 GTPase; GB1 subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Antilisterial Antiparasitic Antiprotozoal Anti-Gram-positive Hydrolase Non-hemolytic
Listeria monocytogenes (Gram-positive)
RECORD: Rec_0226527 VERIFIED: NO
Provenance & Taxonomy
Chlorocebus aethiops [Animal]
TRAFAC class dynamin-like GTPase; GB1 RHD3 GTPase; GB1 subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Antilisterial Antiparasitic Antiprotozoal Anti-Gram-positive Hydrolase Non-hemolytic
Toxoplasma gondii
RECORD: Rec_0244493 VERIFIED: NO
Provenance & Taxonomy
Chlorocebus aethiops [Animal]
TRAFAC class dynamin-like GTPase; GB1 RHD3 GTPase; GB1 subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Antilisterial Antiparasitic Antiprotozoal Anti-Gram-positive Hydrolase Non-hemolytic
Mycobacterium bovis (Gram-positive)