Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length204 amino acids

Chemical FormulaC1037H1570N230O318S10

DescriptionStandard

        LSVLCNIEYFALSTPLTVLRPIDDLTEVDYSLNSLPAVFQPFIDLDLKGIVYPAGNYTNPPYVAAPFTLPDQSDSMLYLAFSEYFFQTSSFAYYTTGAFNITITEETCSYFNMSTEIFGSIIPEVAEYSITPYPVMLKLMATETPIVSLEQDSFTVEIQGSMEVFAVLPDSTTQSLFTMNIAANTSIAPNIFDQKLMGSLCLNR
    

Molecular Weight22667.56 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-17.24

Net Charge (pH 7.4) -17.54

Charge Density (pH 7.0) -0.0845

GRAVY Index0.28

Hydrophobic Moment 0.70

Boman Index0.24

Instability Index50.03

Aliphatic Index 92.75

Aromaticity 0.1324

Extinction Coeff. Reduced 17880.00

Extinction Coeff. Oxidized 18005.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0085820 VERIFIED: NO

Provenance & Taxonomy

OrganismBrachypteracias leptosomus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria