Peptide Database

Peptide NameC-type natriuretic peptide

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC93H157N29O28S3

DescriptionStandard

        GPSRSCFGLKLDRIGAMSGLGC
    

Molecular Weight2225.61 Da

Isoelectric Point (pI)8.96

Net Charge (pH 7.0)1.74

Net Charge (pH 7.4) 1.51

Charge Density (pH 7.0) 0.0791

GRAVY Index0.23

Hydrophobic Moment 0.45

Boman Index0.10

Instability Index66.81

Aliphatic Index 75.45

Aromaticity 0.0455

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 913.44

LogP -11.59

H-bond Donors 35.0

H-bond Acceptors 33.0

Rotatable Bonds 74.0

Heavy Atoms 153.0

Ring Count 2.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0069910 VERIFIED: YES

Provenance & Taxonomy

OrganismSqualus acanthias [Animal]

FamilyC-type natriuretic peptide

Tax ID7797

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-22

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation Receptor modulation

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0273956 VERIFIED: NO