Peptide Database

Peptide NameBrain natriuretic peptide-32

Function Ontology

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC152H256N50O41S4

DescriptionStandard

        SPKMMHKSGCFGRRLDRIGSLSGLGCNVLRKY
    

Molecular Weight3568.23 Da

Isoelectric Point (pI)10.45

Net Charge (pH 7.0)5.52

Net Charge (pH 7.4) 5.23

Charge Density (pH 7.0) 0.1726

GRAVY Index-0.39

Hydrophobic Moment 0.78

Boman Index-0.15

Instability Index79.57

Aliphatic Index 70.00

Aromaticity 0.0625

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1492.51

LogP -16.74

H-bond Donors 57.0

H-bond Acceptors 52.0

Rotatable Bonds 123.0

Heavy Atoms 247.0

Ring Count 4.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0212167 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis familiaris [Animal]

Tax ID9615

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide10-26

Bio-Activity Profile

Function

Neuropeptide

RECORD: Rec_0334652 VERIFIED: YES

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyNatriuretic peptide

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Natriuretic

MethodRadioimmunoassay

Half-LifeInjected intravenously into dogs, in vivo; 94.2 s