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MYP_080915
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Basic Information
Jindongenin-1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
24 amino acids
C111H199N29O33S4
Standard
Sequence
DSMGAVKLAKLLIDKMKCEVTKAC
Physicochemical Analysis
2596.20 Da
8.79
1.74
1.50
0.0725
0.28
0.57
0.03
30.61
101.67
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1015.08
-8.07
37.0
39.0
94.0
177.0
0.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0319646 VERIFIED: YES
Provenance & Taxonomy
Amolops jingdongensis [Animal]
Jindongenin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
18-24
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
17.0 μM
MIC
PaperZ. Chen et al. / Biochimie 94 (2012) 328-334. Two novel families of antimicrobial peptides from skin secretions of the Chinese torrent frog, Amolops jingdongensis Evidence URLhttps://www.uniprot.org/uniprotkb/G3F826/entry
RECORD: Rec_0337960 VERIFIED: YES
Provenance & Taxonomy
Amolops jingdongensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Antifungal
E. cloacae ATCC 13047
40 μM
MIC
PaperTwo novel families of antimicrobial peptides from skin secretions of the Chinese torrent frog, Amolops jingdongensis
RECORD: Rec_0342611 VERIFIED: YES
Provenance & Taxonomy
Amolops jingdongensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Antifungal
Klebsiella pneumoniae ATCC 700603
15 μM
MIC
PaperTwo novel families of antimicrobial peptides from skin secretions of the Chinese torrent frog, Amolops jingdongensis
RECORD: Rec_0345523 VERIFIED: YES
Provenance & Taxonomy
Amolops jingdongensis [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
18-24
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Cytotoxic
PMID21816202 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21816202/
RECORD: Rec_0347624 VERIFIED: YES
Provenance & Taxonomy
Amolops jingdongensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli IS 218#
>200 μg/mL
MIC
PaperTwo novel families of antimicrobial peptides from skin secretions of the Chinese torrent frog, Amolops jingdongensis
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