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MYP_080892
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Basic Information
3
Antimicrobial
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HCMV
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Standard
20 amino acids
C94H153N23O30
Standard
Sequence
EQVLKAVTNVLSPVFPGGET
Physicochemical Analysis
2085.36 Da
4.53
-1.16
-1.33
-0.0581
0.24
0.63
0.23
42.98
102.00
0.0500
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
846.13
-8.38
27.0
29.0
65.0
147.0
3.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0032066 VERIFIED: YES
Provenance & Taxonomy
Human betaherpesvirus 5 [Virus]
Virus-derived peptide
10359;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Replication inhibitor
Human cytomegalovirus (Disrupt UL54/UL44 interaction); Sf9
280 μM
ELISA
PaperInhibition of human cytomegalovirus DNA polymerase by C-terminal peptides from the UL54 subunit. | Loregian A, Rigatti R, Murphy M, Schievano E, Palu G, Marsden HS. | J Virol. 2003 | PMID:12857903 PMID12857903 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12857903/
RECORD: Rec_0061463 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
human cytomegalovirus(HCMV):inhibition of phyical interaction between UL54 and UL44
280 μM
IC50
PaperPubMed PMID: 12857903 PMID12857903 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12857903/
RECORD: Rec_0292606 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0324662 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HCMV
Human cytomegalovirus(HCMV)
280 μM
IC50
Mammalian: 1 h; Yeast: 30 min; E. coli: >10 h
PaperInhibition of human cytomegalovirus DNA polymerase by C-terminal peptides from the UL54 subunit. | Loregian A, Rigatti R, Murphy M, Schievano E, Palu G, Marsden HS. | J Virol. 2003 Aug;77(15):8336-44. | DOI:10.1128/jvi.77.15.8336-8344.2003 | PMID:12857903 PMID12857903 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12857903/
RECORD: Rec_0401892 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 12857903 PMID12857903 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12857903/