Peptide Database

Peptide NameCrotamine

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC169H269N51O45S6

DescriptionStandard

        HCSPKEKICLPPSSDFGKMDCRWRWKCCKKGSGK
    

Molecular Weight3927.65 Da

Isoelectric Point (pI)9.41

Net Charge (pH 7.0)5.80

Net Charge (pH 7.4) 5.46

Charge Density (pH 7.0) 0.1705

GRAVY Index-1.04

Hydrophobic Moment 0.45

Boman Index-0.30

Instability Index82.03

Aliphatic Index 22.94

Aromaticity 0.0882

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1556.27

LogP -15.83

H-bond Donors 60.0

H-bond Acceptors 58.0

Rotatable Bonds 131.0

Heavy Atoms 271.0

Ring Count 9.0

Amide Bonds 33.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0122572 VERIFIED: YES

Provenance & Taxonomy

OrganismCrotalus durissus [Animal]

FamilyCrotamine

Tax ID8731

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Toxin Non-hemolytic Non-ribosomal