Peptide Database

Peptide NameHeV F HRC derived peptide(449-484)

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-Influenza virus

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC177H292N46O63S

DescriptionStandard

        VYTDKVDISSQISSMNQSLQQSKDYIKEAQKILDTV
    

Molecular Weight4104.55 Da

Isoelectric Point (pI)4.78

Net Charge (pH 7.0)-1.26

Net Charge (pH 7.4) -1.49

Charge Density (pH 7.0) -0.0351

GRAVY Index-0.58

Hydrophobic Moment 0.69

Boman Index-0.11

Instability Index45.61

Aliphatic Index 91.94

Aromaticity 0.0556

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1833.24

LogP -21.52

H-bond Donors 62.0

H-bond Acceptors 63.0

Rotatable Bonds 145.0

Heavy Atoms 287.0

Ring Count 2.0

Amide Bonds 41.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0385504 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyProtein-derived synthetic peptide

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Anti-Influenza virus Fusion inhibition

Targethuman parainfluenza virus 3 (HPIV3) | HeLa cells

Activity10 μM

MethodIC50

Half-LifeMammalian: 100 h; Yeast: >20 h; E. coli: >10 h

RECORD: Rec_0424144 VERIFIED: YES