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MYP_080833
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Basic Information
Beta-defensin 106A (Beta-defensin 6, BD-6; primates, mammals, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Standard
45 amino acids
C212H355N61O66S7
Standard
Sequence
FFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCCRTIQPCGSIID
Physicochemical Analysis
5038.91 Da
8.55
2.70
2.37
0.0599
-0.40
0.59
-0.13
14.00
71.56
0.0444
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2104.93
-24.00
77.0
76.0
178.0
346.0
3.0
50.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0022716 VERIFIED: YES
Provenance & Taxonomy
Pan troglodytes [Animal]
Defensin
9598
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial
PaperPubMed PMID: 15904491 | PubMed PMID: 16033865 PMID15904491;16033865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15904491/
RECORD: Rec_0093342 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]; Pan troglodytes [Animal]
Defensin
9606
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
6-33; 13-27; 17-34
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0181398 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
beta-defensin family
9606; 0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
6-33; 13-27; 17-34
Bio-Activity Profile
Antimicrobial beta-defensin family Antibacterial Host defense Defensin-like
PaperPDB 2LWL structural record; NMR; chain A; residues 1-45
RECORD: Rec_0209119 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0256239 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://www.uniprot.org/uniprotkb/Q8N104/entry
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