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MYP_080819
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Basic Information
Dermaseptin-3 (DShypo03; Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
34 amino acids
C151H246N42O44
Standard
Sequence
ALWKDVLKKIGTVALHAGKAAFGAAADTISQGGS
Physicochemical Analysis
3353.82 Da
9.53
1.88
1.64
0.0553
0.32
0.65
0.23
6.56
97.94
0.0588
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1370.78
-14.34
48.0
47.0
112.0
237.0
4.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0063252 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa hypochondrialis [Animal]
Dermaseptin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPubMed PMID: 16844081 PMID16844081 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16844081/
RECORD: Rec_0172483 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa hypochondrialis [Animal]
Dermaseptin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Evidence URLhttps://www.uniprot.org/uniprotkb/P84598/entry
RECORD: Rec_0185931 VERIFIED: YES
Provenance & Taxonomy
Northern orange-legged [Animal]
Dermaseptin
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID16844081 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16844081/
RECORD: Rec_0186672 VERIFIED: NO
Provenance & Taxonomy
Pithecopus hypochondrialis [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal
Qualitative functional evidence
PMID16844081 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16844081/; https://www.uniprot.org/uniprotkb/P84598/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0199621 VERIFIED: YES
Provenance & Taxonomy
Pithecopus hypochondrialis [Animal]
Dermaseptin
317381
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
PaperNovel dermaseptins from Phyllomedusa hypochondrialis (Amphibia).
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