Peptide Database

Peptide NameConotoxin SII-22

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC82H131N27O30S6

DescriptionStandard

        GCCCNPACGPNYGCGTSCSRTL
    

Molecular Weight2167.47 Da

Isoelectric Point (pI)7.78

Net Charge (pH 7.0)0.70

Net Charge (pH 7.4) 0.41

Charge Density (pH 7.0) 0.0318

GRAVY Index0.00

Hydrophobic Moment 0.36

Boman Index0.06

Instability Index52.82

Aliphatic Index 22.27

Aromaticity 0.0455

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 906.07

LogP -16.53

H-bond Donors 37.0

H-bond Acceptors 37.0

Rotatable Bonds 63.0

Heavy Atoms 145.0

Ring Count 3.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0089513 VERIFIED: NO

Provenance & Taxonomy

OrganismConus striatus [Animal]

FamilyConotoxin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0418338 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 0.0%, E 0.0%, T 50.0%, C 50.0% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic