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MYP_080756
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Basic Information
DEFENSIN domain-containing protein
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Fungicidal activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
96 amino acids
C469H754N134O135S8
Standard
Sequence
MRTLVILAAILLVALQAQAEPLQARTDEATAAQEQIPTDNPEVVVSLAWDESLAPKDSVPGLRKNMACYCRIPACLAGERRYGTCFYRRRVWAFCC
Physicochemical Analysis
10686.34 Da
7.55
0.46
0.13
0.0048
0.07
0.60
0.03
65.96
93.65
0.0729
15470.00
15845.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
4312.96
-39.54
156.0
144.0
343.0
746.0
15.0
102.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0006149 VERIFIED: NO
Provenance & Taxonomy
Macaca mulatta [Animal]
Defensin
9544
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic Non-ribosomal
Qualitative functional evidence
PaperGenome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques PMID22002653 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22002653/; https://www.uniprot.org/uniprotkb/G7N0F7/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0116893 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Alpha-defensin; Defensin
9544
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Defensin Antifungal Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Staphylococcus aureus (Gram-positive)
PMID10531277 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10531277/
RECORD: Rec_0122417 VERIFIED: NO
Provenance & Taxonomy
Macaca mulatta [Animal]
Defensin
9544
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperNeutrophil defensin 3 (RMAD-3) Evidence URLhttps://www.uniprot.org/uniprotkb/P60031/entry
RECORD: Rec_0160768 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Alpha-defensin; Defensin
9544
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Defensin Antifungal Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Listeria monocytogenes (Gram-positive)
PMID10531277 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10531277/
RECORD: Rec_0252888 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Alpha-defensin; Defensin
9544
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Defensin Antifungal Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Escherichia coli (Gram-negative)
PMID10531277 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10531277/
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