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MYP_080754
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Basic Information
Bacteriocin lactococcin MMFII
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Listeria
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
37 amino acids
C183H280N48O58S2
Standard
Sequence
TSYGNGVHCNKSKCWIDVSELETYKAGTVSNPKDILW
Physicochemical Analysis
4144.60 Da
6.43
-0.53
-0.82
-0.0144
-0.54
0.29
0.00
27.62
68.38
0.1081
13980.00
14105.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1727.01
-18.47
62.0
61.0
134.0
291.0
8.0
39.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0214132 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
PaperBACTIBASE second release: a database and tool platform for bacteriocin characterization PMID20105292 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20105292/
RECORD: Rec_0223908 VERIFIED: YES
Provenance & Taxonomy
Lactococcus lactis subsp. lactis [Bacterium]
Bacteriocin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Listeria ivanovii
PMID11555873 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11555873/
RECORD: Rec_0231573 VERIFIED: YES
Provenance & Taxonomy
Lactococcus lactis [Bacterium]
Bacteriocin
1358
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
9-14
Bio-Activity Profile
Antimicrobial
ion at 2.5 uM)
PaperLactoccin MMFII, a novel class IIA bacteriocin produced by Lactococcus lactis MMFII, isolated from a Tunisian dairy product
RECORD: Rec_0294426 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0333200 VERIFIED: NO
Provenance & Taxonomy
Lactococcus lactis [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 2023/0416797 A1 Evidence URLhttps://patents.google.com/patent/US20230416797A1/en PatentUS 2023/0416797 A1
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