Peptide Database

Peptide NameLysozyme (EC 3.2.1.17)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length170 amino acids

Chemical FormulaC817H1317N235O235S11

DescriptionStandard

        MSSIIKRCSVAAVLALAVLMPDFRLLKTSPDGLALIADLEGCRLTPYQCSAGVWTSGIGHTAGVVPKGDITEREAAANLVADVLNTERRLAVCVPVTMPQPVYDALVSFSFNVGTGAACRSTLVSYIKRHQWWQACDQLTRWVFVNGTRNKGLENRRARELAYCMKGVTQ
    

Molecular Weight18544.35 Da

Isoelectric Point (pI)9.10

Net Charge (pH 7.0)5.62

Net Charge (pH 7.4) 5.17

Charge Density (pH 7.0) 0.0331

GRAVY Index0.12

Hydrophobic Moment 0.63

Boman Index0.07

Instability Index45.56

Aliphatic Index 94.65

Aromaticity 0.0706

Extinction Coeff. Reduced 27960.00

Extinction Coeff. Oxidized 28335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7528.99

LogP -77.62

H-bond Donors 273.0

H-bond Acceptors 254.0

Rotatable Bonds 603.0

Heavy Atoms 1298.0

Ring Count 25.0

Amide Bonds 181.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0046325 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella pneumoniae [Bacterium]

FamilyLysozyme

Tax ID573

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic

MethodQualitative functional evidence