Peptide Database

Peptide NameP5 Cyclic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC97H145N31O34S2

DescriptionStandard

        YYNPLPHDCGRDNNTDICSR
    

Molecular Weight2353.51 Da

Isoelectric Point (pI)5.30

Net Charge (pH 7.0)-1.17

Net Charge (pH 7.4) -1.46

Charge Density (pH 7.0) -0.0586

GRAVY Index-1.38

Hydrophobic Moment 0.42

Boman Index-0.32

Instability Index29.25

Aliphatic Index 39.00

Aromaticity 0.1000

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1073.21

LogP -13.98

H-bond Donors 38.0

H-bond Acceptors 36.0

Rotatable Bonds 71.0

Heavy Atoms 164.0

Ring Count 5.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0407318 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative

TargetEscherichia coli W3110

Activity4 μM

MethodMBC

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