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MYP_080686
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Basic Information
CF-sC18
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
16 amino acids
C92H168N34O20
Standard
Sequence
GLRKRLRKFRNKIKEK
Physicochemical Analysis
2070.53 Da
12.00
7.76
7.55
0.4849
-1.88
0.65
-0.87
65.72
73.12
0.0625
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
957.91
-7.88
36.0
28.0
80.0
146.0
1.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0044215 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Carboxyfluorescein
None
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID21956822 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21956822/
RECORD: Rec_0052396 VERIFIED: NO
Provenance & Taxonomy
CAMP cathelicidin (106-121) [other]
Protein-derived CPP
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
Amidation
N-term detail: Labelled with fluoresceine
Bio-Activity Profile
Cell-penetrating peptide Antimicrobial
HeLa; HEK 293; MCF-7
Fluorescence-based uptake assay
Evidence URLhttps://crdd.osdd.net/raghava/cppsite/display.php?details=1506
RECORD: Rec_0063490 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Micrococcus luteus DSM 20030
25 μM
MIC50
PMID30389988;25428117 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30389988/
RECORD: Rec_0064061 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus
5 μM
MIC
PMID30389988;25428117 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30389988/
RECORD: Rec_0074176 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Sc18
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
Amidation
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID21956822 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21956822/
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