Peptide Database

Peptide NameLantibiotic nisin-U

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length55 amino acids

Chemical FormulaC247H408N70O80S7

DescriptionStandard

        MNNEDFNLDLIKISKENNSGASPRITSKSLCTPGCKTGILMTCPLKTATCGCHFG
    

Molecular Weight5862.76 Da

Isoelectric Point (pI)8.36

Net Charge (pH 7.0)1.54

Net Charge (pH 7.4) 1.19

Charge Density (pH 7.0) 0.0280

GRAVY Index-0.20

Hydrophobic Moment 0.39

Boman Index0.02

Instability Index25.75

Aliphatic Index 67.45

Aromaticity 0.0364

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2416.21

LogP -31.48

H-bond Donors 87.0

H-bond Acceptors 90.0

Rotatable Bonds 196.0

Heavy Atoms 404.0

Ring Count 6.0

Amide Bonds 59.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0236626 VERIFIED: YES

Provenance & Taxonomy

OrganismStreptococcus uberis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram Positive Bacteria

RECORD: Rec_0325183 VERIFIED: NO