Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length126 amino acids

Chemical FormulaC615H990N174O189S9

DescriptionStandard

        MKLLLLALPILVLLPQVIPAYGGEKKCWNRSGHCRKQCKDGEAVKETCKNHRACCVPSNEDHRRFPTTSPTPLSDSTPGIIDNILTIRFTTDYFEISSKKDMVEESEAGGWESGREVNKEKTQPCL
    

Molecular Weight14134.08 Da

Isoelectric Point (pI)7.57

Net Charge (pH 7.0)0.72

Net Charge (pH 7.4) 0.21

Charge Density (pH 7.0) 0.0057

GRAVY Index-0.55

Hydrophobic Moment 0.55

Boman Index-0.10

Instability Index61.40

Aliphatic Index 73.49

Aromaticity 0.0556

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5842.27

LogP -61.39

H-bond Donors 207.0

H-bond Acceptors 202.0

Rotatable Bonds 471.0

Heavy Atoms 987.0

Ring Count 21.0

Amide Bonds 133.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0143088 VERIFIED: NO

Provenance & Taxonomy

OrganismMacaca fascicularis [Animal]

FamilyBeta-defensin; Defensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic