Peptide Database

Peptide NameP. sarana Hepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC124H190N36O35S8

DescriptionStandard

        QSHLSLCRYCCSCCKNYKGCGYCCKF
    

Molecular Weight3001.58 Da

Isoelectric Point (pI)8.72

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.38

Charge Density (pH 7.0) 0.1447

GRAVY Index-0.12

Hydrophobic Moment 0.53

Boman Index-0.09

Instability Index29.62

Aliphatic Index 30.00

Aromaticity 0.1538

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1167.02

LogP -13.87

H-bond Donors 50.0

H-bond Acceptors 48.0

Rotatable Bonds 97.0

Heavy Atoms 203.0

Ring Count 5.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0281072 VERIFIED: YES

Provenance & Taxonomy

OrganismNothobranchius furzeri [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)