Peptide Database

Peptide NameCycloviolacin O5

Function Ontology

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Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC126H190N32O40S6

DescriptionStandard

        PCGESCVYIPCITGVLGCSCSHNVCYYN
    

Molecular Weight2985.44 Da

Isoelectric Point (pI)5.25

Net Charge (pH 7.0)-1.01

Net Charge (pH 7.4) -1.22

Charge Density (pH 7.0) -0.0362

GRAVY Index0.55

Hydrophobic Moment 0.23

Boman Index0.28

Instability Index35.15

Aliphatic Index 72.86

Aromaticity 0.1071

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1120.01

LogP -13.22

H-bond Donors 45.0

H-bond Acceptors 46.0

Rotatable Bonds 88.0

Heavy Atoms 204.0

Ring Count 6.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0154256 VERIFIED: YES

Provenance & Taxonomy

OrganismViola tricolor [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)