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MYP_080464
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Basic Information
Basic phospholipase A2 BnpTX-1 (BnPTx-I) (svPLA2) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Enzyme / Catalytic activity ▸ Hydrolase
Enzyme modulation ▸ Enzyme inhibition ▸ Blood coagulation cascade inhibitor
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
50 amino acids
C257H374N66O65S7
Standard
Sequence
DLWQFGKMILKVAGKLPFPYYGAYGCYCGWGGRGKPKDPTDRCCFVHDCC
Physicochemical Analysis
5652.58 Da
8.61
2.78
2.43
0.0557
-0.27
0.63
0.07
20.29
46.80
0.1800
16960.00
17335.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2061.66
-14.25
77.0
76.0
174.0
395.0
16.0
50.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0026107 VERIFIED: YES
Provenance & Taxonomy
Bothrops pauloensis [Animal]
Phospholipase A2; Group II subfamily; D49 sub-subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Hydrolase Blood coagulation cascade inhibitor Toxin Cytotoxic Non-hemolytic
Staphylococcus aureus (Gram-positive)
PMID15302537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15302537/
RECORD: Rec_0093670 VERIFIED: YES
Provenance & Taxonomy
Bothrops pauloensis [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
disulfide bond reported, sites not specified
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923
PMID15302537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15302537/
RECORD: Rec_0226925 VERIFIED: YES
Provenance & Taxonomy
Bothrops neuwiedi pauloensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 29648
PMID15302537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15302537/
RECORD: Rec_0237545 VERIFIED: YES
Provenance & Taxonomy
Bothrops pauloensis [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
disulfide bond reported, sites not specified
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC29648 and Gram-positive bacterium: S
PMID15302537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15302537/
RECORD: Rec_0331888 VERIFIED: YES
Provenance & Taxonomy
Bothrops neuwiedi pauloensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923
PMID15302537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15302537/
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