‹ ›
MYP_080428
← PREVIOUS NEXT → BACK
Basic Information
Ocellatin-P1 (Pentadactylin)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
25 amino acids
C112H200N30O34S
Standard
Sequence
GLLDTLKGAAKNVVGSLASKVMEKL
Physicochemical Analysis
2543.03 Da
9.53
1.76
1.55
0.0704
0.37
0.53
0.15
-16.79
124.80
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1044.18
-9.96
36.0
37.0
91.0
177.0
0.0
25.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0312592 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pentadactylus [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Streptococcus group B
50 μM
MIC
PMID16236555 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16236555/
RECORD: Rec_0315486 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
400 μM
LD50
Paperhttps://pubmed.ncbi.nlm.nih.gov/16236555/ PMID16236555 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16236555/
RECORD: Rec_0318159 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pentadactylus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Staphylococcus epidermidis RP62A
100 μM
MIC
PaperPentadactylin: an antimicrobial peptide from the skin secretions of the South American bullfrog Leptodactylus pentadactylus PMID16236555
RECORD: Rec_0319109 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus pentadactylus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Enterobacter cloacae HNTCC 53001
50 μM
MIC
PaperPentadactylin: an antimicrobial peptide from the skin secretions of the South American bullfrog Leptodactylus pentadactylus PMID16236555
RECORD: Rec_0324127 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
FIRST PREV 1 ... 4 5 6 7 NEXT LAST
Showing 5 records · Page 6 of 7